Research & Independent Study Students

Current:


   
Qianshu Wang (BBMB 2017) -  Investigations of improved mounting methods for maximum SAD efficiency.

Kaitlin Harrison (BBMB 2018) -  Investigations of improved mounting methods for maximum SAD efficiency.

Nick Wechter (BBMB 2016) -  Investigations and modeling of soaking induced cracking in protein crystals.

Tim Grote (Physics/Pre-Engineering 2018) -  Arduino-based temperature controller for humidity control device.



Past:

Jeremiah Jurich (BBMB 2016) -  The use of molecular dynamics to determine thermal contraction of binary solutions of cryoprotective agents.

Christopher Farley (Physics/Bio-Engineering 2016) -  Dehydration based variation in protein crystals. Vapor-diffusion based cryoprotection.

Walker Larson (Physics 2014) - Interferometry based approaches for measurement of thermal expansion of liquids.

Geoff Burks (BBMB 2013) -  Investigations of optimal mounting methods for protein cryocrystallography.

Rose Cotter (BBMB 2013) - Testing a thermal contraction model for guiding cryoprotectant choice in macromolecular crystallography. 

Conor Holton-Burke (BBMB 2011) - Testing a thermal contraction model for guiding cryoprotectant choice in protein         cryocrystallography.

Jon Ruffin (Math & Physics, 2013) - Measurements of thermal contraction of liquids using volume displacement and interferometry.

Olivia Ware (BBMB 2013) - Cryogenic behavior of the lipidic cubic phase; diffusion through pores of protein crystals.

Chris Saxby (BBMB 2011) - Testing a thermal contraction model for guiding cryoprotectant choice in protein cryocrystallography, liquid thermal expansion measurements using volume displacement and interferometry, viscosity measurement
   
Fritz Siegert (BBMB 2012) - Investigations of thermal contraction as a predictor for the efficacy of external oils as cryoprotectants in protein cryocrystallography.

Kelly Jensen (BBMB 2012) - TMAO/sarcosine mixtures as precipitating agents for protein crystal growth.

Christa Heavey (Math-Physics 2012) - Diffusion through pores of protein crystals.

Kel Peyton (BBMB 2012) - Purification and crystallization of PcpA (with Tim Machonkin, Chemistry)

Nang San Hti Lar Seng (BBMB 2011) - The use of stabilizing osmolytes (TMAO, sarcosine & betaine) as cryoprotectants for protein crystallography.

Haley Marshall (BBMB 2010) - Investigations of the use of stabilizing osmolytes as precipitants for protein crystallography.

Murugappan Venkat (Physics & Economics 2012) - Investigations of the use of stabilizing osmolytes as precipitants for protein crystallography.


Jackson Cahn (BBMB 2010) -

Investigation of a conformational change that occurs in crystals of MntR as a function of pH, time and temperature. In collaboration with Arthur Glasfeld,     Chemistry, Reed College.
The use of stabilizing osmolytes as precipitating agents for protein crystallography.
Testing a thermal contraction model for cryoprotectant choice.

Allison Ikeda (BBMB 2011) - Investigations of clouding that occurs when the lipidic cubic phase is cryocooled. 

Group Summer 2010

Summer 2010 - from left to right: Doug Juers, Murugu Venkat, Jackson Cahn, Haley Marshall

Tracey Park (BBMB 2008) - Investigations of the role of the depletion effect in PEG induced protein crystallization.

 

Rob Jefferson (BBMB 2008) - structural studies of MBP-Calmodulin fusion constructs.

 

 

 

 

Jessica Bruhn (BBMB 2009) - Perry Award for structural studies of MBP-Actin fusion constructs

 

 

 

 

 

Thuy Dao (BBMB 2007) - PIRL1 structural studies; phase diagram of lyzosyme crystallization; self-interaction chromatography to measure PEG induced protein-protein interactions. Now in PhD program in Biophysics at Johns Hopkins University.

 

 

 

 

Thomas Alcorn (BBMB 2007) - Thermal contraction of binary mixtures of water and cryoprotectants

Matt Queral (BBMB 2007) - Cloning of myelin basic protein constructs

Kyle Gotchy (left, English 2007) - Abshire Award to study the phase diagram of trypsin crystallization & purification; crystallization of E. coli b-galactosidase for cryo-cooling experiments. Now at U Washington Law School.

Celia Hagan (right, BBMB 2007) - purification & crystallization of E. coli b-galactosidase for cryo-cooling experiments. Now studying for Masters in Public Health at Johns Hopkins University.

 

 

 

 

 

Gary LiMarzi (BBMB 2007) - Identification of solution conditions favoring trypsin crystal stability.

Marc Leroueil (BBMB 2006) - Solubility of ternary solutions of PEG & salts.

Lauren Berndt (BBMB 2005)

 

Collaborators & Coauthors